| Item Type | Name |
|
Concept
|
Algorithms
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Computer Graphics
|
|
Concept
|
Cell Count
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Cell Movement
|
|
Concept
|
DNA Damage
|
|
Concept
|
Bacterial Proteins
|
|
Concept
|
Binding Sites
|
|
Concept
|
Biological Transport
|
|
Concept
|
Biomechanical Phenomena
|
|
Concept
|
Cell Division
|
|
Concept
|
Cell Cycle
|
|
Concept
|
DNA Repair
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Obesity
|
|
Concept
|
Enzyme Induction
|
|
Concept
|
Germ Cells
|
|
Concept
|
Membrane Proteins
|
|
Concept
|
Models, Genetic
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Necrosis
|
|
Concept
|
Gonads
|
|
Concept
|
Mutation
|
|
Concept
|
Selection, Genetic
|
|
Concept
|
Membrane Fusion
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Protein Binding
|
|
Concept
|
Protein Conformation
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Proteins
|
|
Concept
|
Homeostasis
|
|
Concept
|
Time Factors
|
|
Concept
|
Thermodynamics
|
|
Concept
|
Sequence Homology, Amino Acid
|
|
Concept
|
Viral Fusion Proteins
|
|
Concept
|
Ultraviolet Rays
|
|
Concept
|
Drug Resistance, Neoplasm
|
|
Concept
|
Protein Structure, Quaternary
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Mutagenesis
|
|
Concept
|
Membrane Fluidity
|
|
Concept
|
Ion Channel Gating
|
|
Concept
|
Molecular Conformation
|
|
Concept
|
Porosity
|
|
Concept
|
Gene Expression
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Anisotropy
|
|
Concept
|
Immediate-Early Proteins
|
|
Concept
|
Apoptosis
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
ras Proteins
|
|
Concept
|
Gene Regulatory Networks
|
|
Concept
|
Calcium Signaling
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Gene Knockout Techniques
|
|
Concept
|
Protein Structure, Secondary
|
|
Concept
|
Protein Folding
|
|
Concept
|
Clonal Evolution
|
|
Concept
|
Chromosomal Instability
|
|
Concept
|
Periplasmic Binding Proteins
|
|
Concept
|
Genome, Helminth
|
|
Concept
|
Smad4 Protein
|
|
Concept
|
Amino Acid Substitution
|
|
Concept
|
Amino Acid Motifs
|
|
Concept
|
Catalytic Domain
|
|
Concept
|
Enzyme Activators
|
|
Concept
|
BRCA2 Protein
|
|
Concept
|
Vesicle-Associated Membrane Protein 2
|
|
Concept
|
bcl-X Protein
|
|
Concept
|
Databases, Protein
|
|
Concept
|
Receptors, Glucocorticoid
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Rotation
|
|
Concept
|
Structure-Activity Relationship
|
|
Concept
|
Platelet Membrane Glycoprotein IIb
|
|
Concept
|
Mechanical Phenomena
|
|
Concept
|
Static Electricity
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Temperature
|
|
Concept
|
Protein Multimerization
|
|
Concept
|
Hydrophobic and Hydrophilic Interactions
|
|
Concept
|
Cell Death
|
|
Concept
|
Viral Proteins
|
|
Concept
|
Fusion Proteins, bcr-abl
|
|
Concept
|
Dimerization
|
|
Concept
|
Metabolic Networks and Pathways
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Caenorhabditis elegans Proteins
|
|
Concept
|
Drug Resistance, Viral
|
|
Concept
|
Cell Cycle Checkpoints
|
|
Concept
|
Transcriptome
|
|
Concept
|
Escherichia coli Proteins
|
|
Concept
|
Tumor Microenvironment
|
|
Concept
|
Organogenesis
|
|
Concept
|
Homologous Recombination
|
|
Concept
|
Receptor, Fibroblast Growth Factor, Type 3
|
|
Concept
|
G Protein-Coupled Inwardly-Rectifying Potassium Channels
|
|
Concept
|
Amyloid Precursor Protein Secretases
|
|
Concept
|
Protein Stability
|
|
Concept
|
Diet, High-Fat
|
|
Concept
|
Carrier Proteins
|
|
Concept
|
Cell Survival
|
|
Concept
|
Genotype
|
|
Concept
|
Kinetics
|
|
Concept
|
Movement
|
|
Concept
|
Phenotype
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Archaeal Proteins
|
|
Concept
|
Genomics
|
|
Concept
|
Membrane Potential, Mitochondrial
|
|
Concept
|
Molecular Dynamics Simulation
|
|
Academic Article
|
Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.
|
|
Academic Article
|
Dynamite: a simple way to gain insight into protein motions.
|
|
Academic Article
|
Characterization of protein conformational states by normal-mode frequencies.
|
|
Academic Article
|
Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.
|
|
Academic Article
|
Simulations of a protein translocation pore: SecY.
|
|
Academic Article
|
Accommodation of a central arginine in a transmembrane peptide by changing the placement of anchor residues.
|
|
Academic Article
|
Mechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles.
|
|
Academic Article
|
Exploring peptide-membrane interactions with coarse-grained MD simulations.
|
|
Academic Article
|
A helix heterodimer in a lipid bilayer: prediction of the structure of an integrin transmembrane domain via multiscale simulations.
|
|
Academic Article
|
Structural flexibility of the macrophage dengue virus receptor CLEC5A: implications for ligand binding and signaling.
|
|
Academic Article
|
The energetics of transmembrane helix insertion into a lipid bilayer.
|
|
Academic Article
|
Bookshelf: a simple curation system for the storage of biomolecular simulation data.
|
|
Academic Article
|
Coarse-grain simulations reveal movement of the synaptobrevin C-terminus in response to piconewton forces.
|
|
Academic Article
|
Multi-scale simulation of the simian immunodeficiency virus fusion peptide.
|
|
Academic Article
|
Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling.
|
|
Academic Article
|
How lipid headgroups sense the membrane environment: an application of ¹4N NMR.
|
|
Academic Article
|
Changes in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations.
|
|
Academic Article
|
Drug target optimization in chronic myeloid leukemia using innovative computational platform.
|
|
Academic Article
|
Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer.
|
|
Academic Article
|
Role of the C-terminal domain in the structure and function of tetrameric sodium channels.
|
|
Academic Article
|
Primary and secondary dimer interfaces of the fibroblast growth factor receptor 3 transmembrane domain: characterization via multiscale molecular dynamics simulations.
|
|
Academic Article
|
Logic programming to predict cell fate patterns and retrodict genotypes in organogenesis.
|
|
Academic Article
|
Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors.
|
|
Academic Article
|
Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death.
|
|
Academic Article
|
Probing the Solution Structure of I?B Kinase (IKK) Subunit ? and Its Interaction with Kaposi Sarcoma-associated Herpes Virus Flice-interacting Protein and IKK Subunit ß by EPR Spectroscopy.
|
|
Academic Article
|
Emergent stem cell homeostasis in the C. elegans germline is revealed by hybrid modeling.
|
|
Academic Article
|
Probing the solution structure of I?B kinase (IKK) subunit ? and its interaction with Kaposi sarcoma-associated herpes virus Flice-interacting protein and IKK subunit ß by EPR spectroscopy.
|
|
Academic Article
|
Coarse-Grained MD Simulations and Protein-Protein Interactions: The Cohesin-Dockerin System.
|
|
Academic Article
|
Relating evolutionary selection and mutant clonal dynamics in normal epithelia.
|
|
Academic Article
|
Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.
|
|
Academic Article
|
Exploring the role of stromal osmoregulation in cancer and disease using executable modelling.
|
|
Academic Article
|
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
|
|
Academic Article
|
A toolbox for discrete modelling of cell signalling dynamics.
|
|
Academic Article
|
Cellular survival over genomic perfection.
|
|
Academic Article
|
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
|
|
Academic Article
|
Constructing and Analyzing Computational Models of Cell Signaling with BioModelAnalyzer.
|
|
Academic Article
|
Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance.
|
|
Academic Article
|
SARS-CoV-2 Variants Are Selecting for Spike Protein Mutations That Increase Protein Stability.
|
|
Academic Article
|
Simulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia.
|
|
Academic Article
|
HOXA9 has the hallmarks of a biological switch with implications in blood cancers.
|
|
Academic Article
|
The NALCN channel regulates metastasis and nonmalignant cell dissemination.
|
|
Academic Article
|
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition.
|
|
Academic Article
|
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.
|
|
Concept
|
ADAM10 Protein
|
|
Concept
|
Voltage-Gated Sodium Channels
|
|
Concept
|
Spike Glycoprotein, Coronavirus
|
|
Concept
|
Osmoregulation
|
|
Concept
|
Cellular Reprogramming
|
|
Academic Article
|
Mutations observed in somatic evolution reveal underlying gene mechanisms.
|
|
Academic Article
|
Author Correction: Somatic mutations in facial skin from countries of contrasting skin cancer risk.
|
|
Academic Article
|
SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma.
|
|
Academic Article
|
Somatic mutations in facial skin from countries of contrasting skin cancer risk.
|
|
Academic Article
|
KCNQ potassium channels modulate Wnt activity in gastro-oesophageal adenocarcinomas.
|
|
Academic Article
|
Interpreting the effect of mutations to protein binding sites from large-scale genomic screens.
|
|
Academic Article
|
Large-scale computational modelling of the M1 and M2 synovial macrophages in rheumatoid arthritis.
|
|
Academic Article
|
Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations.
|
|
Academic Article
|
Understanding large scale sequencing datasets through changes to protein folding.
|